Although choline may not be one of the most glamorous or common topics in the media today relating to health and wellness, but the fact is, it’s a nutrient that’s imperative for health and wellness and you must not assume you are getting enough of it. Known as an important macronutrient, choline supports one’s body in exactly the same way as your vital B-vitamins. Choline becomes necessary for your liver and nerve functioning, muscle movement, energy, and also a healthy metabolism. What’s more, it is important for the brain’s normal development, function and health.
Choline is found in food that naturally include certain fats, thus it is found in many animal products, such as beef, liver, salmon, and eggs. You need to get enough choline (not often an easy feat from food alone) to be able to help support a slew of systems throughout your body, which include your digestive, endocrine, nervous, and reproductive systems. Choline also helps the body form DNA and cell structures, and maintain healthy liver function. The truth is, without an adequate absorption of choline, you could become at risk of chronic liver damage and even liver failure.
Choline’s Impact on Memory and Brain Function.
One of choline’s key advantages is its capability to ensure your brain cognitively keeps you sharp minded as you age. Due to the involvement with cell membranes and neurotransmitters, choline helps preserve your memory and prevent dementia, memory loss and other forms of cognitive decline as you grow older. Choline helps your brain maintain its “elasticity” by supporting acetylcholine levels, which diminish because you age. Lower levels of acetylcholine can result in cognitive decline and related cognitive degeneration conditions – patients with Alzheimer’s disease sometimes show low levels of acetylcholine.
According to the National Center for Biotechnology Information (NCBI), choline may be used to treat a number of diseases belonging to the central nervous system and mental health, including depression, memory loss, Alzheimer’s disease and dementia, Huntington’s chorea, Tourette’s disease, a brain disorder called cerebellar ataxia, several types of seizures, and even schizophrenia.
In a recent study supplementing daily with CDP Choline (Citicoline) has been shown to improve focus, enrgy, enhance mood, memory recall and memory retention in the over 50’s.
Are you Deficient in Choline?
Depending on your genes, physiology and whether you have a digestive disorder, you might not be able to absorb choline optimally, that can put you vulnerable to choline deficiency. Also, because it is found in many animal products, vegans and vegetarians may eventually be at risk of choline deficiency. Indications of choline deficiency include, but aren’t restricted to: cognitive decline, loss of memory, learning disabilities, fatigue, mood changes, muscle aches, and/or nerve damage.
CDP-Choline (INN), also known as cytidine diphosphate-choline (Citicoline) or cytidine 5′-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.
CDP-Choline is the most effective Choline Source For Cognitive Benefits.
Warning: Not all sources of choline are the same. Choline is the “basic” form (also known as “basic choline”) and is usually purchased as “bitartrate.” Basic choline is simply that-the most “basic” and cheap type of choline. It is much less expensive than CDP-choline and for that reason, it is used considerably more often in various supplements. Basic choline doesn’t effectively cross the blood-brain barrier and doesn’t reliably increase neural (brain) concentrations of choline. Although the basic type of choline does have some benefits to your liver and can improve methylation, its benefits are certainly lacking with regards to helping the brain.
Another basic kind of choline is “choline citrate.” This form can offer about 50% more choline content than choline bitartrate and can have some other health benefits, such as assisting in prevention of fatty deposits from accumulating within the liver. Unfortunately, also, it is ineffective at crossing the blood-brain barrier or increasing choline concentrations in the brain.
CDP-choline offers the body with usable choline which will increase neural concentrations of choline much better than either form of basic choline. CDP-choline has the ability to be transformed into both choline and uridine, thereby allowing you to really benefit from both cognitive enhancing molecules which have been shown to help protect the brain from damage and may also have a positive effects on learning. CDP-choline supplementation, as opposed to basic choline, can protect against the progression of memory deficits, and long-term CDP-choline supplementation is shown to be strongly linked to the prevention of memory impairment.
What the Research Suggests: CDP-Choline Supports Memory and Ability to Focus
Studies have shown that CDP-choline offers numerous neuroprotective benefits, together with supporting your brain’s ability to focus. In one research study, 16 healthy adults were administered CDP-choline for 6 weeks at doses of 500mg to 2000mg. The researchers found that CDP-choline supplementation triggered beneficial changes in phosphate metabolism and cell membrane turnover in the frontal lobes of the brains of the research participants. Interestingly, the degree of these beneficial changes was larger in the research participants who took the 500mg dose, compared to those that took the 2000mg dose.
The study findings on the neuroprotective of CDP-choline are similar to the results of other studies that have looked at the clinical benefits of CDP-choline supplementation. One example is, a research study of 60 adult women found an every day dosage of 250mg or 500mg of CDP-choline significantly improved the participants’ focus. Along with providing benefits to the brain in older adults, there is also research that shows CDP-choline provides benefits to the brain in older and aging adults. One study showed that dosages of 500mg to 1000mg of CDP-choline improved memory performance in older adults with memory deficits (this research, however, does not relate to individuals with Alzheimer’s disease).
There isn’t any doubt that getting an adequate amount of choline is very important to your health and wellness, as well as the relationship between CDP-choline specifically and the advantages to brain health are significant